“Diuretics are a family of drugs that make the body hold less water,” Professor Layton said.
“Being dehydrated is a major factor in acute kidney injury, and then the RAS inhibitor and ibuprofen hit the kidney with this triple whammy. If you happen to be on these hypertension drugs and need a painkiller, consider acetaminophen instead.”
Other reasons to avoid ibuprofen
According to the NHS, you should not take ibuprofen by mouth or apply it to your skin if you have ever had an allergic reaction or symptoms like wheezing, runny nose or skin reactions after taking aspirin, ibuprofen or other non-Steroidal anti-inflammatory drugs (NSAIDs) such as naproxen.
You should also avoid the painkiller if you’re pregnant, the health body adds.
