A New Technology of Coronavirus Exams Is Coming. Right here's What to Count on.


Nonetheless, the short exams obtainable now are often inaccurate. Though they “guarantee we will get a solution quicker,” stated Dr. Ibukun Akinboyo, a pediatrician and infectious illness specialist at Duke College’s College of Drugs, “you lose some sensitivity,” she stated. “It’s arduous to win at each.”

Final month, a swab-based point-of-care take a look at referred to as Abbott ID Now made headlines when an evaluation discovered that it’d miss infections as much as 48 p.c of the time, regardless of being promoted by President Trump as “extremely correct.”

Sensitivity points additionally plague antigen exams, which detect items of proteins made by the virus, fairly than its genes. Antigen exams have been used to detect different airway infections, such because the flu, in lower than an hour, and are simple to fabricate en masse. However the comfort comes at a value: Not like genetic materials, antigens can’t be amplified simply. Some antigen exams, together with just a few that seek for influenza viruses, fail to choose up on energetic infections around 50 percent of the time.

“If a Covid antigen take a look at performs like an influenza antigen take a look at, I don’t suppose they’ll have a lot utility,” stated Dr. David Alland, the director of the Middle for Rising Pathogens at Rutgers New Jersey Medical College. Nonetheless, he famous, “if improved, they may very well be very promising.”

Even imprecise exams have their place on this pandemic, so long as they’re simple to make use of and distributed broadly sufficient. Ought to a take a look at “miss somebody on Monday, perhaps you’ll get them a day or two later,” Dr. Wyllie stated.

Thus far, solely two firms have acquired emergency authorization from the F.D.A. for coronavirus antigen exams. One is Quidel, which is, in accordance with a consultant, producing hundreds of thousands of exams every month, lots of which have been distributed to pressing care facilities and medical clinics in america. On Monday, a second agency, Becton Dickinson & Firm, additionally entered the fray with a point-of-care antigen take a look at that may reportedly produce results in 15 minutes. Whereas speedy, each Quidel’s and BD’s exams could produce false negatives between 15 and 20 percent of the time.


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